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Esophageal reflux, also known as acid reflux or gastroesophageal reflux disease (GERD), is a digestive ailment marked by the reflux of stomach acid and/or contents into the esophagus, the tube that connects the throat to the stomach. Occasional reflux is typical and might happen after eating large meals, spicy or acidic foods, or lying down just after eating. However, frequent or persistent reflux symptoms may suggest GERD, a chronic condition that can cause consequences if not managed.
The major cause of esophageal reflux is failure of the lower esophageal sphincter (LES), a muscular ring positioned at the esophageal-gastric junction. Normally, the LES acts as a barrier, keeping stomach contents from refluxing into the esophagus. When the LES relaxes or weakens abnormally, stomach acid and digestive fluids can back up into the esophagus, causing irritation, inflammation, and symptoms like heartburn, regurgitation, chest pain, difficulty swallowing, and coughing.
Hiatal hernia (a condition in which a portion of the stomach protrudes into the chest cavity through the diaphragm), obesity, pregnancy, smoking, alcohol consumption, certain medications (e.g., nonsteroidal anti-inflammatory drugs, calcium channel blockers), and certain medical conditions can all contribute to esophageal reflux.
Esophageal reflux symptoms might vary in severity and frequency depending on the individual. Heartburn, a burning sensation or discomfort in the chest that worsens after eating or lying down; regurgitation, the sensation of sour or bitter-tasting fluid rising from the stomach into the throat or mouth; difficulty swallowing (dysphagia); chronic cough; hoarseness; sore throat; and angina-like chest pain.
Esophageal reflux is typically diagnosed using a medical history, physical examination, and diagnostic tests such as upper gastrointestinal (GI) endoscopy, esophageal pH monitoring, esophageal manometry, and imaging studies to assess the extent of esophageal inflammation and for complications such as Barrett’s esophagus (a precancerous condition).
Treatment for esophageal reflux seeks to relieve symptoms, minimize esophageal irritation and inflammation, avoid complications, and enhance quality of life. Lifestyle changes such as keeping a healthy weight, avoiding trigger foods and beverages (e.g., spicy, acidic, fatty foods, caffeine, alcohol), eating smaller meals, not lying down immediately after eating, and elevating the head of the bed can all help lessen reflux symptoms.
In addition to lifestyle changes, medicines may be administered to decrease stomach acid production, neutralize stomach acid, strengthen the LES, or increase esophageal motility. Proton pump inhibitors (PPIs), H2 receptor antagonists (H2 blockers), antacids, and prokinetic medicines are among the most commonly prescribed GERD treatments. In situations with severe or resistant GERD, surgical intervention such as fundoplication (wrapping the top of the stomach around the LES to strengthen its function) or LINX device placement (implantation of a magnetic ring around the LES to prevent reflux) may be explored.
To summarize, esophageal reflux, also known as gastroesophageal reflux disease (GERD), is a common digestive ailment defined by the drainage of stomach acid into the esophagus, causing symptoms such as heartburn, regurgitation, and chest pain. Individuals suffering from GERD can effectively manage their symptoms and avoid complications with correct diagnosis and treatment, which may include lifestyle changes, medications, and, in some circumstances, surgery.
References:
1.American College of Gastroenterology. (2022). Gastroesophageal Reflux Disease (GERD). Retrieved from https://gi.org/topics/gerd/
2.Mayo Clinic. (2022). GERD (Gastroesophageal Reflux Disease). Retrieved from https://www.mayoclinic.org/diseases-conditions/gerd/symptoms-causes/syc-20361940
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